“No coopora nisi
fluida”, the terms depicts extent and need of solvent for a chemical reaction
to proceed, was coined by Greece Philosopher Aristotle.
However, it has
now been found that reactions to an extent may occur even in solventless
environment where host reactant and attacking reagent directly comes in contact
with each other.
Both the techniques
when compared in terms of synthetic scenario have their own pros and cons
nevertheless use of solvent to assist a chemical reaction is still
unquestionable owing to their decisive direct influence on outcomes such as
reaction rate, product purity, its yield, economic value, and eco-friendly
technique.
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